HOW TO FIND THE PERFECT REMEDY FOR HIGH BLOOD PRESSURE?
IT IS IMPORTANT TO UNDERSTAND THAT FINDING A SUITABLE DRUG IS SOMETIMES LONG AND ARDUOUS PROCESS AND IT IS RECOMMENDED PATIENCE AND PERSEVERANCE.
Diuretics
Diuretics or 'water tablets' acting on the kidney so that they secrete a major amount of water and salt, and thereby lowering the blood pressure. Experts for hypertension recommend the introduction of diuretics as 'first-line' therapy for hypertension. Appendix diuretics any other antihypertensive enhances its activity and is often used in combination with ACE inhibitors, calcium channel blockers, beta blockers, and 'Santana'. In people over 80 years is a good choice diuretic indapamide because it reduces the risk of stroke, heart failure and other cardiovascular diseases.
Beta Blockers
This class of drugs reduces cardiac afterload, opens blood vessels and lowers the heart rate. Work well in combination with a diuretic. (Atenolol, propranolol, metoprolol, bisoprolol, nebivolol)
Inhibitors of angiotensin enzyme inhibitors (ACE inhibitors)
Ace inhibitors relax blood vessels and play a particularly important role in patients with coronary artery disease, heart failure, renal insufficiency, and in diabetics. The effect is enhanced by the addition of a diuretic (Lisinopril, Ramipril, enalapril, perindopril, quinapril, eosinophil)
Angiotensin receptor blockers "tartans" (because the name ends in Santana: telmisartan, losartan, eprosartan, valsartan)
They look similar to ACE inhibitors: relax blood vessels and are useful in patients with coronary heart disease, diabetes, and cardiac and renal failure.
Calcium channel blockers
This group of drugs relax the smooth muscles of blood vessels (amylopsin, lacidipine, nifedipine) and some slow the heart rate (verapamil, diltiazem). It is known interactions with grapefruit juice so caution with grapefruit lovers!
The latest group of drugs:
Renin inhibitors (aliskiren): reduces the production of renin, an enzyme is very important in the regulation of blood pressure. Do not include still in standard therapy.
Alpha blockers: widen blood vessels (doxazosin)
Centrally acting drugs: effect on brain centers that regulate blood pressure (moxonidine)
Often the question is which drug to choose the initial screening for blood pressure control. JNC (Joint National Commission) is recommended to start with a lower dose of diuretics, especially for isolated systolic hypertension, and in the elderly. ACE inhibitors are the treatment of choice for diabetics, people with heart failure and myocardial infarction. In the case to develop a cough as a side effect of treatment with ACE inhibitors, "Spartans' are a good choice.
When you achieve optimum pressure control continue to take medication: IT IS ESSENTIAL TO TAKE DAILY THERAPY, NOT IF NECESSARY and are checked regularly by a competent physician.
It is useful to occasionally do, and 24 h Halter pressure that records blood pressure in a 24 hour period which facilitates physician administering treatment.
Recent studies have shown that the combination of drugs is better than using one drug at the maximum dose (diuretic in combination with an ACE inhibitor, a beta blocker, losartan). The combination of some type calcium blockers and beta blockers can cause bradycardia and extreme caution is needed.
It is important to understand that finding the right medication is sometimes long and arduous process and it is recommended patience and perseverance as adequate therapy to prevent complications, morbidity and death from cardiovascular disease.
Bibliography:
Washington Manual: Hypertension
Harrison's: Internal Medicine
Sir Sharma, MD, FRCPC, Professor: Hypertension Overview
Mayo Clinic: Hypertension, information for patients
SOURCE:
Mireya Cvijanovic al. honey.
Specialist in Internal Medicine
Medical Clinic, Zagreb
IT IS IMPORTANT TO UNDERSTAND THAT FINDING A SUITABLE DRUG IS SOMETIMES LONG AND ARDUOUS PROCESS AND IT IS RECOMMENDED PATIENCE AND PERSEVERANCE.
Diuretics
Diuretics or 'water tablets' acting on the kidney so that they secrete a major amount of water and salt, and thereby lowering the blood pressure. Experts for hypertension recommend the introduction of diuretics as 'first-line' therapy for hypertension. Appendix diuretics any other antihypertensive enhances its activity and is often used in combination with ACE inhibitors, calcium channel blockers, beta blockers, and 'Santana'. In people over 80 years is a good choice diuretic indapamide because it reduces the risk of stroke, heart failure and other cardiovascular diseases.
Beta Blockers
This class of drugs reduces cardiac afterload, opens blood vessels and lowers the heart rate. Work well in combination with a diuretic. (Atenolol, propranolol, metoprolol, bisoprolol, nebivolol)
Inhibitors of angiotensin enzyme inhibitors (ACE inhibitors)
Ace inhibitors relax blood vessels and play a particularly important role in patients with coronary artery disease, heart failure, renal insufficiency, and in diabetics. The effect is enhanced by the addition of a diuretic (Lisinopril, Ramipril, enalapril, perindopril, quinapril, eosinophil)
Angiotensin receptor blockers "tartans" (because the name ends in Santana: telmisartan, losartan, eprosartan, valsartan)
They look similar to ACE inhibitors: relax blood vessels and are useful in patients with coronary heart disease, diabetes, and cardiac and renal failure.
Calcium channel blockers
This group of drugs relax the smooth muscles of blood vessels (amylopsin, lacidipine, nifedipine) and some slow the heart rate (verapamil, diltiazem). It is known interactions with grapefruit juice so caution with grapefruit lovers!
The latest group of drugs:
Renin inhibitors (aliskiren): reduces the production of renin, an enzyme is very important in the regulation of blood pressure. Do not include still in standard therapy.
Alpha blockers: widen blood vessels (doxazosin)
Centrally acting drugs: effect on brain centers that regulate blood pressure (moxonidine)
Often the question is which drug to choose the initial screening for blood pressure control. JNC (Joint National Commission) is recommended to start with a lower dose of diuretics, especially for isolated systolic hypertension, and in the elderly. ACE inhibitors are the treatment of choice for diabetics, people with heart failure and myocardial infarction. In the case to develop a cough as a side effect of treatment with ACE inhibitors, "Spartans' are a good choice.
When you achieve optimum pressure control continue to take medication: IT IS ESSENTIAL TO TAKE DAILY THERAPY, NOT IF NECESSARY and are checked regularly by a competent physician.
It is useful to occasionally do, and 24 h Halter pressure that records blood pressure in a 24 hour period which facilitates physician administering treatment.
Recent studies have shown that the combination of drugs is better than using one drug at the maximum dose (diuretic in combination with an ACE inhibitor, a beta blocker, losartan). The combination of some type calcium blockers and beta blockers can cause bradycardia and extreme caution is needed.
It is important to understand that finding the right medication is sometimes long and arduous process and it is recommended patience and perseverance as adequate therapy to prevent complications, morbidity and death from cardiovascular disease.
Bibliography:
Washington Manual: Hypertension
Harrison's: Internal Medicine
Sir Sharma, MD, FRCPC, Professor: Hypertension Overview
Mayo Clinic: Hypertension, information for patients
SOURCE:
Mireya Cvijanovic al. honey.
Specialist in Internal Medicine
Medical Clinic, Zagreb